Novel Drugs Targeting the Epidermal Growth Factor Receptor and Its Downstream Pathways in the Treatment of Colorectal Cancer: A Systematic Review
Figure 1
Schematic diagram showing various drugs acting on EGFR and its subsequent pathways. MEK: MAPK (mitogen-activated protein kinase) kinases/extracellular-signal-regulated kinases, ERK: extracellular-signal-related kinase; PTEN: phosphatase and tensin homolog, mTOR: mammalian target of rapamycin.