Lomustine Analogous Drug Structures for Intervention of Brain and Spinal Cord Tumors: The Benefit of In Silico Substructure Search and Analysis

Table 2

Property statistics.

Property	Mean	Minimum	Maximum	Median	Standard deviation
Log P	2.524	1.537	3.924	2.458	0.5337
Polar surface area (A^2)	62.89	61.77	82.0	61.77	4.768
Number of atoms	14.5	12	17	14.5	1.465
Molecular weight	232.8	191.6	312.6	225.7	30.76
Number of O & N	5	5	6	5	0.2357
Number of –OH and –NH𝑛	1	1	2	1	0.2357
Violations of Rule of 5	0	0	0	0	0
Number of rotatable bonds	2.3	4	8	5	1.274
Volume (A^3)	202.4	163.1	246.5	201.5	23.03