Clinical Study

Dose-Dense Epirubicin and Cyclophosphamide Followed by Weekly Paclitaxel in Node-Positive Breast Cancer

Table 2

Incidence of toxicities in treated patients.

ToxicitiesG2 number (%)G4 number (%)

Haematological toxicity
 Neutropenia11 (18.3)
 Febrile neutropenia1 (1.7)
 Anemia14 (23.3)
 Thrombocytopenia3 (5)
Nonhaematological toxicity
 Skin-nail disorders1 (1.7)3 (5)
 Scaling
 Stomatitis
 Hand-foot syndrome
 Erythema
 Paresis
 Paresthesia2 (3.3)7 (11.7)
 Myalgia9 (15)2 (3.3)
 Arthralgia4 (6.7)2 (3.3)
 Nausea6 (10)2 (3.3)
 Vomiting
 Diarrhea2 (3.3)
 Fluid retention1 (1.7)

Any grade 4 event9 (15)