Table of Contents
Chemotherapy Research and Practice
Volume 2014, Article ID 520701, 8 pages
http://dx.doi.org/10.1155/2014/520701
Clinical Study

A Postauthorization Survey to Document the Therapeutic Management of Oxaliplatin as a First-Line Chemotherapy Regimen in South Africa in Patients with Metastatic Colorectal Cancer

1Department of Medical Oncology, Faculty of Medical Sciences, University of Pretoria, Prinshof Campus, Steve Biko Academic Hospital, Dr. Savage Road, Pretoria 0001, South Africa
2Medical Department, Sanofi South Africa, Midrand 1682, South Africa

Received 13 January 2014; Revised 19 March 2014; Accepted 19 March 2014; Published 10 April 2014

Academic Editor: Vassilis Georgoulias

Copyright © 2014 Lydia M. Dreosti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, “Global cancer statistics,” CA: Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. C.-H. Köhne, G. Folprecht, R. M. Goldberg, E. Mitry, and P. Rougier, “Chemotherapy in elderly patients with colorectal cancer,” Oncologist, vol. 13, no. 4, pp. 390–402, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. N. Mqoqi, P. Kellett, F. Sitas et al., Cancer in South Africa, 1998-1999, National Cancer Registry of South Africa, Johannesburg, South Africa, 2004.
  4. M. M. Center, A. Jemal, R. A. Smith, and E. Ward, “Worldwide variations in colorectal cancer,” CA: Cancer Journal for Clinicians, vol. 59, no. 6, pp. 366–378, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. D. L. Bartlett and E. Chu, “Can metastatic colorectal cancer be cured?” Oncology, vol. 26, no. 3, pp. 266–275, 2012. View at Google Scholar · View at Scopus
  6. J. Norstein and W. Silen, “Natural history of liver metastases from colorectal carcinoma,” Journal of Gastrointestinal Surgery, vol. 1, no. 5, pp. 398–407, 1997. View at Google Scholar · View at Scopus
  7. C. Tournigand, T. André, E. Achille et al., “FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study,” Journal of Clinical Oncology, vol. 22, no. 2, pp. 229–237, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. M. L. Rothenberg, A. M. Oza, R. H. Bigelow et al., “Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial,” Journal of Clinical Oncology, vol. 21, no. 11, pp. 2059–2069, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. A. de Gramont, A. Figer, M. Seymour et al., “Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer,” Journal of Clinical Oncology, vol. 18, no. 16, pp. 2938–2947, 2000. View at Google Scholar · View at Scopus
  10. S. Giacchetti, B. Perpoint, R. Zidani et al., “Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer,” Journal of Clinical Oncology, vol. 18, no. 1, pp. 136–147, 2000. View at Google Scholar · View at Scopus
  11. E. Aitini, A. Rossi, P. Morselli et al., “Economic comparison of capecitabine + oxaliplatin and 5-fluorouracil + oxaliplatin in the adjuvant treatment of colon cancer,” Cancer Management and Research, vol. 4, no. 1, pp. 99–103, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. H. T. Arkenau, D. Arnold, J. Cassidy et al., “Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials,” Journal of Clinical Oncology, vol. 26, pp. 5910–5917, 2008. View at Google Scholar
  13. “Common Terminology Criteria for Adverse Events v3. 0 (CTCAE),” 2006.
  14. M. M. Oken, R. H. Creech, and T. E. Davis, “Toxicology and response criteria of the Eastern Cooperative Oncology Group,” The American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 5, no. 6, pp. 649–655, 1982. View at Google Scholar · View at Scopus
  15. R. M. Goldberg, M. L. Rothenberg, E. Van Cutsem et al., “The continuum of care: a paradigm for the management of metastatic colorectal cancer,” Oncologist, vol. 12, no. 1, pp. 38–50, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Y. Douillard, D. Cunningham, A. D. Roth et al., “Irinotecan combined with fluorouracil compared with fluorouracil alone. as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial,” The Lancet, vol. 355, no. 9209, pp. 1041–1047, 2000. View at Google Scholar · View at Scopus
  17. S. R. Alberts, D. J. Sargent, S. Nair et al., “Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial,” Journal of the American Medical Association, vol. 307, no. 13, pp. 1383–1393, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. E. Gamelin, L. Gamelin, L. Bossi, and S. Quasthoff, “Clinical aspects and molecular basis of oxaliplatin neurotoxicity: current management and development of preventive measures,” Seminars in Oncology, vol. 29, supplement 15, no. 5, pp. 21–33, 2002. View at Google Scholar · View at Scopus
  19. A. Grothey, “Oxaliplatin-safety profile: neurotoxicity,” Seminars in Oncology, vol. 30, supplement 15, no. 4, pp. 5–13, 2003. View at Google Scholar · View at Scopus
  20. J. Cassidy, S. Clarke, E. Díaz-Rubio et al., “XELOX vs FOLFOX-4 as first-line therapy for metastatic colorectal cancer: NO16966 updated results,” British Journal of Cancer, vol. 105, no. 1, pp. 58–64, 2011. View at Publisher · View at Google Scholar · View at Scopus