The Triglyceride to HDL Ratio and Its Relationship to Insulin Resistance in Pre- and Postpubertal Children: Observation from the Wausau SCHOOL Project

Table 2

Clinical characteristics: TG/HDL ratio <3 compared to ≥3.

Characteristic	TG/HDL ratio <3	TG/HDL ratio ≥3	P value
TC (mg/dl)	173.0  ±  28.6	180.2  ±  38.5	P  = 0.294
LDL (mg/dl)	115.4  ±  25.6	120.0  ±  32.2	P  = 0.352
HDL (mg/dl)	48.3  ±  9.2	36.7  ±  7.0	P  < 0.001
LDL # (nmol/L)	1147.3  ±  238.0	1353.9  ±  388.2	P  = 0.004
LDL Size (nm)	21.5  ±  .36	20.9  ±  .56	P  < 0.001
HOMA-IR	1.46  ±  1.29	3.29  ±  4.3	P  = 0.017
QUICKI	.38  ±  .04	.34  ±  .03	P  < 0.001
WH ratio	.84  ±  .10	.86  ±  .09	P  = 0.269
zBMI	.22  ±  1.39	1.03  ±  1.05	P  = 0.001
BP-systolic (mmHg)	105.0  ±  14.9	117.2  ±  15.4	P  < 0.001
BP-diastolic (mmHg)	65.9  ±  9.8	70.2  ±  8.2	P  = 0.014
Glucose (mg/dl)	83.7  ±  6.2	86.0  ±  7.0	P  = 0.050
% with elevated BP	34 (17%)	15 (43%)	P  = 0.001

TG: triglyceride, TC: total cholesterol, LDL: low-density lipoprotein, HDL: high-density lipoprotein, LDL #: no. of LDL particles, LDL Size: Size of LDL particles, HOMA-IR: homeostasis model assessment of insulin resistance, QUICKI: quantitative insulin sensitivity check index, WH: waist hip, zBMI: age- and sex- corrected body mass index, TG/HDL: ratio of TG to HDL, BP-systolic: systolic blood pressure, BP-diastolic: diastolic blood pressure.
^*All P values are based on independent t-tests, except the last, which is based on a Chi-square with 1 df. Elevated BP is defined as systolic >120 or diastolic >80.