The Influence of an Obesogenic Diet on Oxysterol Metabolism in C57BL/6J Mice

Table 3

Oxysterol levels in control and high fat-cholesterol diets.

Variables	ND	HFC
4β-OH	0.10±0.01	0.17±0.06
5,6β-Epoxy	0.36±0.05	0.60±0.35
5,6α-Epoxy	0.34±0.05	0.82±0.51
7-keto	0.84±0.04	0.72±0.08^∗
7α-OH	0.64±0.47	0.94±0.12
7β-OH	1.09±0.06	0.95±0.50
25-OH	0.21±0.18	0.37±0.05
27-OH	0.02±0.01	1.95±0.20^†

Note. Data are present as mean ± SD, 𝑛=5 per group. ^∗𝑃<0.05, ^†𝑃<0.001. Oxysterols are presented as ng/mg of chow. 7α-OH: 7α-hydroxycholesterol; 7β-OH: 7β-hydroxycholesterol; 7-keto: 7-ketocholesterol; 4β-OH: 4β-hydroxycholesterol; 5,6α-epoxy: 5,6α-epoxycholesterol; 5,6β-epoxy: 5,6β-epoxycholesterol; 25-OH: 25-hydroxycholesterol; 27-OH: 27-hydroxycholesterol.