Research Article

Identification of Quantitative Trait Loci That Determine Plasma Total-Cholesterol and Triglyceride Concentrations in DDD/Sgn and C57BL/6J Inbred Mice

Figure 1

Genome-wide scan for plasma CHO concentrations in F2 male mice. (a) A histogram showing the distribution of plasma CHO concentrations. (b) Genome-wide LOD score plot of single-QTL scans for plasma CHO concentrations (solid lines: cross direction as an additive covariate; broken lines: cross direction and body weight as additive covariates). The -axis represents the Chrs and microsatellite marker positions, and the -axis represents the LOD score. The horizontal broken lines indicate the genome-wide threshold LOD score for significant () and suggestive () linkage, respectively.
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