Table 5: Significant and suggestive QTL for CHO identified by genome-wide scans of combined F2 mice ().

QTLChrPeak cM95% CILODNearest markerHigh strain

Choldq1179.277.5–82.564.7Apoa2DDD
Choldq9341.812.8–62.82.5D3Mit25B6
Choldq4547.817.8–72.02.1D5Mit239DDD
Choldq2821.214.5–53.54.4D8Mit191B6
Choldq121161.434.4–75.43.5D11Mit124DDD
1260.623.0–62.22.5D12Mit141B6
Choldq61719.713.1–49.13.3D17Mit176B6

QTL, quantitative trait loci; CI, confidence interval; LOD, logarithm of the odds.
Sex was included as an additive covariate.
QTL symbols were assigned if they were significant or if they were suggestive but were identified as significant QTL at least once previously in different genetic crosses [9].
95% CI was defined by a 1.5-LOD decrease.
LOD scores for significant QTL are indicated in bold. The threshold LOD scores for significant and suggestive QTL were 3.5 and 2.1, respectively, for autosomes and 3.7 and 2.1, respectively, for Chr X.
High strain-derived allele was associated with higher plasma CHO.