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Computational Intelligence and Neuroscience
Volume 2011, Article ID 852961, 32 pages
Research Article

EEG and MEG Data Analysis in SPM8

1The Wellcome Trust Centre for Neuroimaging, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
2INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Centre, Brain Dynamics and Cognition Team, Lyon, F-69500, France
3Max Planck Institute for Human Cognitive and Brain Sciences, 04303 Leipzig, Germany
4Cyclotron Research Centre, University of Liège, 4000 Liège, Belgium
5MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK
6Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6500 HB Nijmegen, The Netherlands

Received 24 September 2010; Accepted 7 December 2010

Academic Editor: Sylvain Baillet

Copyright © 2011 Vladimir Litvak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


SPM is a free and open source software written in MATLAB (The MathWorks, Inc.). In addition to standard M/EEG preprocessing, we presently offer three main analysis tools: (i) statistical analysis of scalp-maps, time-frequency images, and volumetric 3D source reconstruction images based on the general linear model, with correction for multiple comparisons using random field theory; (ii) Bayesian M/EEG source reconstruction, including support for group studies, simultaneous EEG and MEG, and fMRI priors; (iii) dynamic causal modelling (DCM), an approach combining neural modelling with data analysis for which there are several variants dealing with evoked responses, steady state responses (power spectra and cross-spectra), induced responses, and phase coupling. SPM8 is integrated with the FieldTrip toolbox , making it possible for users to combine a variety of standard analysis methods with new schemes implemented in SPM and build custom analysis tools using powerful graphical user interface (GUI) and batching tools.