A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays

Figure 11

Example of a continuous measurement for several hours performed with the devised MEA interface system coupled to an environmental chamber to preserve cell viability. The three snapshots represent the 60-channel raw voltage activity over 10-minute segments relative to three different moments during the recording, that is, after 1, 13, and 26 hours (as indicated on the left). Green frame, silent channel (only background noise). Red frame, spiking channel.