Novel Methods for Measuring Depth of Anesthesia by Quantifying Dominant Information Flow in Multichannel EEGs

Figure 4

Transfer entropy of various bipartitions in clinical multichannel EEGs. (a) Raw multichannel EEGs for 140 min before and after anesthesia, (b) plasma concentration of propofol (infusion rate = 12 mg/kg/h), (c) transfer entropy for arbitrary bipartition, (d) transfer entropy for principle bipartition with maximum information flow, (e) transfer entropy for principle bipartition with MIB, and (f) averaged transfer entropy for all possible bipartitions.

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