TY - JOUR A2 - Koundal, Deepika AU - Alazzam, Malik Bader AU - Al-Radaideh, Ahmad Tawfig AU - Binsaif, Nasser AU - AlGhamdi, Ahmed S. AU - Rahman, Md Adnan PY - 2022 DA - 2022/01/07 TI - [Retracted] Advanced Deep Learning Human Herpes Virus 6 (HHV-6) Molecular Detection in Understanding Human Infertility SP - 1422963 VL - 2022 AB - To see if HHV-6 may be a cause of infertility, researchers looked at 18 men and 10 women who had unexplained critical fertility and had at least one prior pregnancy. HHV-6 DNA was discovered in both infertile and fertile peripheral blood mononuclear cells (PBMC) (12 and 14%, respectively); endometrial epithelial cells from 4/10 (40%) infertile women were positive for HHV-6 DNA; this viral DNA was not found in the endometrium of fertile women. When endometrial epithelial cells were cultivated, they produced viral early and late proteins, suggesting the existence of an infectious virus. Endometrial HHV-6 infection creates an aberrant NK cell and cytokine profile, resulting in a uterine domain that is not favorable to conception, according to the findings. To corroborate the findings, studies of extra fertile and barren women should be done. Semen samples were taken from 18 guys who visited the Government General Hospital Guntur’s infertility department because they were having reproductive issues with their partners. Herpes virus DNA has been discovered in the sperm of symptomatic fertile and infertile male patients on rare instances. Furthermore, researchers must investigate the role of viral diseases in male infertility. SN - 1687-5265 UR - https://doi.org/10.1155/2022/1422963 DO - 10.1155/2022/1422963 JF - Computational Intelligence and Neuroscience PB - Hindawi KW - ER -