[Retracted] LncXIST Facilitates Iron Overload and Iron Overload-Induced Islet Beta Cell Injury in Type 2 Diabetes through miR-130a-3p/ALK2 Axis

Figure 4

XIST reversed the protective effects of miR-130a on INS-1 cells. (a) The expression of miR-130a-3p in INS-1 cells transfected with control, vector, miR-130a-3p mimics, and pc-XIST detected by RT-qPCR analysis. (b) Cell proliferation after transfection different time was measured by MTT assay. (c) Representative results of TUNEL staining for every group. Scale bar = 100 μm. (d) GSIS was used to measure the secretion of insulin. (e) The LIP level was detected for every group. (f) The iron metabolic-related protein expression was detected in islet beta cells.  < 0.05,  < 0.01.

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