Table of Contents
Chinese Journal of Biology
Volume 2014 (2014), Article ID 216210, 6 pages
http://dx.doi.org/10.1155/2014/216210
Review Article

Chronic Kidney Disease—Effect of Oxidative Stress

1Department of Biochemistry, Sree Balaji Medical College and Hospital, Bharath University, CLC Works Road, Chrompet, Chennai 600 044, India
2Department of Nephrology, Sree Balaji Medical College and Hospital, Bharath University, CLC Works Road, Chrompet, Chennai 600 044, India

Received 27 September 2013; Accepted 30 October 2013; Published 21 January 2014

Academic Editors: A. Castañeyra-Perdomo, W. Ding, and R. Malli

Copyright © 2014 Subha Palaneeswari Meenakshi Sundaram et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chronic kidney disease (CKD) is a growing health problem with increasing incidence. The annual mortality of end-stage renal disease patients is about 9%, which is 10–20 fold higher than the general population, approximately 50% of these deaths are due to cardiovascular (CV) disease. CV risk factors, such as diabetes, hypertension, and hyperlipidemia, are strongly associated with poor outcome. Many other nontraditional risk factors such as inflammation, infection, oxidative stress, anemia, and malnutrition are also present. In this review we will focus on the role of oxidative stress in chronic kidney disease.