Anticancer Activity of Tabernaemontana coronaria against Carcinogen Induced Clear Cell Renal Cell Carcinoma

Table 2

Effect of T. coronaria on DEN and Fe-NTA induced enhancement of 𝛾-glutamyl transpeptidase, xanthine oxidase, and lactate dehydrogenase in kidney.

Particulars	𝛾-glutamyl transpeptidase	Xanthine oxidase	LDH
Control	389.97±5.53^a	0.35±0.003^a	38.77±1.17^a
DEN + Fe-NTA	692.68±15.84^b	0.68±0.01^b	78.70±1.38^b
DEN and Fe-NTA + 200 mg/kg T. coronaria	523.24±7.48^c	0.51±0.007^c	69.15±1.42^c
DEN and Fe-NTA + 400 mg/kg T. coronaria	446.34±5.17^d	0.4±0.009^d	45.58±1.39^d
T. coronaria alone (200 mg/kg)	394.82±3.26^a	0.34±0.005^a	39.63±0.77^a
T. coronaria alone (400 mg/kg)	383.26±2.86^a	0.32±0.004^a	37.10±0.72^a

Values are expressed as mean ± SD (𝑛=6).
Values not sharing the common superscript (a–d) differ significantly (DMRT).
𝛾-glutamyl transpeptidase, xanthine oxidase—units/mg protein.
LDH, nmoles of pyruvate liberated/min/mg protein.