Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 1987 / Article

Brief Communication | Open Access

Volume 1 |Article ID 954647 |

Michael A Noble, J Scott Whittaker, Anil K Mangal, Cedric J Carter, Hugh J Freeman, "Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome", Canadian Journal of Gastroenterology and Hepatology, vol. 1, Article ID 954647, 3 pages, 1987.

Candida Esophagitis in a Male Homosexual with Defective Neutrophil Function. A 'Pseudo-AIDS' Syndrome

Received11 Mar 1987
Accepted14 May 1987


36-year-old male homosexual presented with a prolonged history of odynophagia. Esophageal candidiasis was suspected at endoscopy and confirmed by biopsy ane cultures. Investigations demonstrated no evidence for underlying human immunodeficiency virus (HIV) infection hy either ELISA assay or Wes1ern Blot technique, and lymphocyte helper: supressor ratios were normal. A specific serum-dependent factor that inhibited the candidacidal capability of his neutrophils, as well as those of volunteer controls, was detected. This inhibitor disappeared after treatment of the candidal infection. Severe and extensive esophagitis is not always indicative of an underlying infection with HIV in homosexual mnles. Clinical criteria alone should not be used to establish the diagnosis of AIDS, even in patients from recognized high risk categories.

Copyright © 1987 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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