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Canadian Journal of Gastroenterology
Volume 2 (1988), Issue 2, Pages 57-59
Clinical Gastroenterology

Clinical and Laboratory Observations on Patients from a Nursing Home Outbreak of Verotoxin-Producing E Coli (157:H7 Strain)

Melvin R. Belsheim, James Lewis, and William Brien

Department of Medicine, St Joseph's Hospital, The Uuniveristy of Western Ontario, London Ontario, Canada

Received 29 September 1987; Accepted 9 February 1988

Copyright © 1988 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Beginning on September 7, 1985, an outbreak of bloody diarrhea affected 53 of 169 residents of a London, Ontario nursing home. The most severely affected patients were transferred to local general hospitals under the care of a number of physicians for investigation and treatment. Overall, 19 patients died during the outbreak. Clinical and laboratory information on the 18 patients admitted to this institution are reported. A majority of these patients had either verotoxin detected in focal extracts or Escherichia coli 0157:H7 isolated from their stools. The mortality rare at this institution exceeded 75% (14 patients). Six patients developed hemolytic uremic syndrome and none of these survived the illness.