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Canadian Journal of Gastroenterology
Volume 2, Issue 2, Pages 75-78
http://dx.doi.org/10.1155/1988/817574
Review

Barrett's Esophagus and Adenocarcinoma

Z.W. Li and A.B.R. Thomson

Nutrition and Metabolism Research Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmnton, Alberta, Canada

Received 1 February 1988; Accepted 1 April 1988

Copyright © 1988 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

As association between Barrett's esophagus and adenocarcinoma of the esophagus is relatively frequent. Survival with adenocarcinoma is generally poor. Routine surveillance endoscopy is suggested with generous biopsy material and brush cytology to detect either high grade dysplasia or intramucosal carcinoma in patients with Barrett's esophagus. Individual cases of high grade dysplasia should be independently confirmed by another pathologist familiar with dysplasia grading. Esophagectomy should be recommended for those patients with high grade dysplasia whose risk for surgery is outweighed by the possible presence or development of cancer.