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Canadian Journal of Gastroenterology
Volume 2, Issue 1, Pages 18-21
Clinical Gastroenterology

5-ASA Therapy in Solitary Rectal Ulcer Syndrome. Report of Three Patients

D.A. Malatjalian and C.N. Williams

Division of Gastroenterology, Departments of Pathology and Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

Received 16 November 1987; Accepted 22 December 1987

Copyright © 1988 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Solitary rectal ulcer syndrome (SRUS) is a rare condition which presents typically with a long standing history of constipation, straining, rectal bleeding, mucus discharge and pain on defecation. Three cases of SRUS arc discussed which were all successfully treated with 5-ASA enemas. Complete healing occurred within a few weeks and recurrent ulcers healed just as readily with renewed therapy.