Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 1989 / Article

Brief Communication | Open Access

Volume 3 |Article ID 498156 |

Gilles Lapointe, Aubin Charbonneau, "Cyclophosphamide: An Alternative Treatment in Crohn’s Disease", Canadian Journal of Gastroenterology and Hepatology, vol. 3, Article ID 498156, 4 pages, 1989.

Cyclophosphamide: An Alternative Treatment in Crohn’s Disease

Received16 May 1989
Accepted17 Aug 1989


lmmunosuppressive therapy in the form of 6-mercaptopurine has shown a 66% efficacy in severe, debilitating, highly corticosteroid dependent Crohn’s disease. Nevertheless this medication has some important side effects such as nausea, vomiting, leukopenia and pancreatitis. Two patients are presented who, suffering from severe Crohn’s disease, were unable to tolerate 6-mercaptopurine but showed an amazing improvement with cyclophosphamide.

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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