Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 1989 / Article

Review | Open Access

Volume 3 |Article ID 601524 |

Samuel W. French, Leslie B. Eidus, J. Freeman, "Nonalcoholic Fatty Hepatitis: An Important Clinical Condition", Canadian Journal of Gastroenterology and Hepatology, vol. 3, Article ID 601524, 9 pages, 1989.

Nonalcoholic Fatty Hepatitis: An Important Clinical Condition

Received21 Jul 1989
Accepted19 Sep 1989


The entity fatty hepatitis is defined and the literature characterizing the clinical settings in which it develops is reviewed. The pathogenesis is discussed with emphasis on the common denominators shared by the various clinical conditions with which it is associated. The roles of alcohol, obesity and type II diabetes are stressed where inhibition of fatty acid oxidation by the liver is the basic defect in metabolism leading to fatty change, balloon degeneration and Mallory body formation. It is concluded that this important entity is more common than is generally appreciated.

Copyright © 1989 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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