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Canadian Journal of Gastroenterology
Volume 5, Issue 4, Pages 129-132
Brief Communication

Cerbral Venous Thrombosis in Ulcerative Colitis and Review of the Literature

Hugh Chaun, Jeff H Beckman, and Terence G Sparling

Divisions of Gastroenterology, Neurology and Hematology, Department of Medicine, University Hospital and University of British Columbia, Vancouver, British Columbia, Canada

Received 25 April 1991; Accepted 3 June 1991

Copyright © 1991 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 30-year-old man with an eight year history of ulcerative colitis developed left occipital headache, mental confusion, dysphasia and right-sided weakness when his bowel disease was asymptomatic. Investigations revealed thrombosis of the cerebral sagittal sinus and left transverse sinus. The literature relating to cerebrovascular complications associated with ulcerative colitis is reviewed, and the possible pathogenetic mechanisms of venous thrombosis in ulcerative colitis are discussed. The importance of recognizing that venous thrombosis may occur in association with ulcerative colitis in remission is emphasized.