Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 1992 / Article

Review | Open Access

Volume 6 |Article ID 743457 |

Daniel Muruve, Ellen Burgess, "Renal Aspects of Peptic Ulcer Pharmacology", Canadian Journal of Gastroenterology and Hepatology, vol. 6, Article ID 743457, 6 pages, 1992.

Renal Aspects of Peptic Ulcer Pharmacology

Received25 Sep 1991
Revised31 Jan 1992


Medications to treat peptic ulcer disease are used widely and may have adverse effects on renal function. Similarly, renal dysfunction may alter the pharmacokinetics of this diverse group of medications resulting in dosage adjustments. The older agents, antacids and sucralfate, allow absorption of cations (calcium, magnesium and aluminum) which may result in toxicity. Newer medications (H2 blockers and omeprazole) appear to have fewer side effects and be better tolerated with appropriate dosage adjustments.

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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