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Canadian Journal of Gastroenterology
Volume 11, Issue 5, Pages 449-450
Brief Communication - Hepatology

Hepatopulmonary Syndrome Associated with Schistosomal Liver Disease

Mohamed Al-Moamary and Ibrahim Altraif

Department of Medicine, Department of Hepatobiliary Sciences, King Fahad National Guard Hospital, Riyadh, Saudi Arabia

Received 11 March 1996; Accepted 24 March 1997

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 55-year-old man with schistosomal liver disease presented with shortness of breath, orthodeoxia, platypnea, cyanosis, marked digital clubbing and liver failure. Extensive investigation revealed no other etiology for liver disease apart from schistosomiases. The diagnosis of hepatopulmonary syndrome was based on clinical grounds, as well as abnormal arterial blood gases and positive contrast echocardiography. The patient underwent orthotopic liver transplantation, which was initially successful, but then died of respiratory complications and multi-organ failure on day 42 post-transplant. To the authors' knowledge this is the first report of hepatopulmonary syndrome associated with schistosomal liver disease.