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Canadian Journal of Gastroenterology
Volume 17, Issue 9, Pages 559-561
http://dx.doi.org/10.1155/2003/415179
Brief Communication

Intestinal Thromboangiitis Obliterans in a Woman: A Case Report and Discussion of Chronic Ischemic Changes

Shaun AC Medlicott,1 Paul Beaudry,2 Gary Morris,3 Gwen Hollaar,2 and Francis Sutherland2

1Calgary Laboratory Services, Peter Lougheed Hospital, University of Calgary, Calgary, Alberta, Canada
2Department of General Surgery, Peter Lougheed Hospital, University of Calgary, Calgary, Alberta, Canada
3Department of Internal Medicine, Peter Lougheed Hospital, University of Calgary, Calgary, Alberta, Canada

Received 26 May 2003; Revised 6 October 2003

Copyright © 2003 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although traditionally regarded as a disease of distal extremities, mesenteric vasculature can also manifest thromboangiitis obliterans (TAO). There are 31 cases of intestinal TAO in the English literature and the majority of subjects are male. However, cases of women with TAO are becoming more common, coinciding with an increased incidence of smoking in this sex. We describe the sixth case of a female patient with classic extremity manifestations paralleled by paroxysms of abdominal angina. Intestinal TAO can mimic extremity disease of smoldering chronic ischemia punctuated by unpredictable acute episodes of gangrene. In the present case, chronic ischemia manifested as partial bowel obstruction due to stricture deformity of the ileum and profound adipocyte atrophy of mesentery.