Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 2009 / Article

Commentary | Open Access

Volume 23 |Article ID 514618 |

Matt Shale, Subrata Ghosh, "Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis", Canadian Journal of Gastroenterology and Hepatology, vol. 23, Article ID 514618, 3 pages, 2009.

Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis

Received14 Jan 2009
Accepted15 Jan 2009


Psoriasis or psoriasiform skin lesions, as an adverse effect of treatment with antitumor necrosis factor antibody therapy, have been described relatively recently. Patients with these lesions have no personal or family history of psoriasis. In a small number of cases, an association with Chlamydia has been suggested. The skin lesions may disappear on discontinuation of therapy or, in the majority of cases, even if antitumor necrosis factor antibody therapy is continued. Therefore, withdrawal of therapy is generally not required for this adverse effect but referral to a dermatologist may be desirable for confirmation of diagnosis and treatment.

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