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Canadian Journal of Gastroenterology
Volume 24 (2010), Issue 1, Pages 58-60
Brief Communication

Sellar Inflammatory Mass with Inflammatory Bowel Disease

Hugh J Freeman and John Maguire

Departments of Medicine (Gastroenterology) and Anatomical Pathology (Neuropathology), University of British Columbia, Vancouver, British Columbia, Canada

Received 16 January 2009; Accepted 21 January 2009

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Inflammatory bowel disease may be associated with different intracranial disorders. An inflammatory sellar mass is very rare but includes a variety of noninfectious causes including lymphocytic hypophysitis, granulomatous inflammation and Wegener’s granulomatosis. A 32-year-old man was diagnosed with an inflammatory sellar mass associated with an extensive colonic inflammatory process clinically characteristic of Crohn’s disease. The concurrent onset of these inflammatory disorders in distinctly separate sites may reflect their common embryological origin or represent an unusual form of metastatic Crohn’s disease. Further studies are needed to determine if less overt or focal sellar inflammatory processes occur in inflammatory bowel disease, particularly in Crohn’s disease because their occurrence may be critically relevant for long-term management.