Canadian Journal of Gastroenterology and Hepatology

Canadian Journal of Gastroenterology and Hepatology / 2010 / Article

Brief Communication | Open Access

Volume 24 |Article ID 943270 |

Brent K Wilde, Jenna-Lynn Senger, Rani Kanthan, "Gastrointestinal Schwannoma: An Unusual Colonic Lesion Mimicking Adenocarcinoma", Canadian Journal of Gastroenterology and Hepatology, vol. 24, Article ID 943270, 4 pages, 2010.

Gastrointestinal Schwannoma: An Unusual Colonic Lesion Mimicking Adenocarcinoma

Received07 Jul 2009
Accepted08 Jul 2009


Gastrointestinal schwannoma is a rare, benign pathological entity that can mimic colonic adenocarcinoma and cause diagnostic dilemmas for treatment. A case of a 68-year-old woman with colonic adenocarcinoma who was discovered to have an incidental synchronous bowel lesion that proved to be a gastrointestinal schwannoma and not a synchronous adenocarcinoma is described. Gastrointestinal schwannomas are uncommon in the colorectal region; they are most often located in the stomach. These spindle cell lesions are distinct from gastrointestinal stromal tumours because the tumour cells have a distinct immunophenotype, with strong diffuse positivity for S-100, glial fibrillary acidic protein and vimentin, and corroborative negative staining of CD34, CD117 and smooth muscle markers. Accurate diagnosis and recognition of this benign entity is, therefore, of immense clinicopathological value for accurate planning of therapeutic strategies.

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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