Research Article

Comparison of One versus Two Fecal Immunochemical Tests in the Detection of Colorectal Neoplasia in a Population-Based Colorectal Cancer Screening Program

Table 1

Positive predictive value of one versus two positive FITs.

PathologyTwo positive FITs PPV (95% CI)One positive FIT PPV (95% CI)Total value

Cancer458% (6%, 11%)131% (1%, 2%)58<0.0001
High-risk polyp21040% (36%, 44%)20920% (18%, 22%)419<0.0001
Any neoplasia35267% (63%, 71%)49948% (45%, 51%)851<0.0001