Research Article

Outcomes following Serial Intragastric Balloon Therapy for Obesity and Nonalcoholic Fatty Liver Disease in a Single Centre

Table 2

Clinical outcomes at 6 months.

Clinical parameterBaseline6 months (after IGB removal)Mean differencep value

Weight (kg)117.9106.611.3<0.01
BMI (kg/m2)41.737.64.1<0.01
Waist circumference (cm)124.2101.123.10.04
Fasting BSL (mmol/L)6.05.40.60.12
Fasting insulin (mIU/L)136.096.539.50.12
HOMA-IR3.62.61.00.03
ALT (IU/L)38.931.07.9<0.01
AST (IU/L)35.132.82.30.11
GGT (IU/L)62.639.123.5<0.01
Fasting cholesterol (mmol/L)4.85.10.08
Fasting LDL (mmol/L)2.72.80.09
Fasting HDL (mmol/L)1.21.5āˆ’0.30.39
Fasting triglycerides (mmol/L)1.81.40.40.22

A significant difference in ALT and GGT was noted at follow-up in those with an elevated HOMA-IR score (i.e., insulin resistance) at baseline.