Research Article
Establishing a Porcine Model of Small for Size Syndrome following Liver Resection
Table 2
Laboratory findings at baseline and during the follow-up period.
| | | | | | | |
| | Albumin (mean [95% CI]) |
| | Group A | 31.5 (28.8–34.1) | 29.5 (26.7–32.2) | 31.2 (28.3–34.1) | 33.3 (31.7–34.8) | 0.016 | | Group B | 30.7 (27.1–34.2) | 23.4 (19.3–27.4) | 30.2 (29.0–31.5) | 27.6 (24.1–31.2) | | Group C | 30.1 (26.3–34.0) | 28.7 (16.2–41.2) | 30.7 (19.4–42.0) | 26.2 (16.1–36.2) | | 0.783 | 0.028 | 0.826 | 0.003 |
| | AST (mean [95% CI]) |
| | Group A | 46.6 (36.5–56.7) | 62.9 (50.3–75.4) | 59.7 (−1.9–121.4) | 29.9 (25.1–34.6) | 0.001 | | Group B | 49.0 (41.0–57.0) | 249.0 (16.8–481.2) | 811.2 (493.3–1129.0) | 276.5 (45.4–507.6) | | Group C | 49.3 (37.9–60.8) | 127.7 (−86.1–341.5) | 502.7 (345.4–659.9) | 541.3 (−610.3–1693.0) | | 0.845 | 0.096 | <0.001 | 0.017 |
| | ALT (mean [95% CI]) |
| | Group A | 41.2 (33.6–48.7) | 39.0 (34.6–43.4) | 54.0 (42.4–65.5) | 37.2 (28.1–46.3) | 0.003 | | Group B | 51.0 (39.7–62.3) | 64.2 (25.7–102.6) | 110.3 (79.8–140.9) | 81.0 (43.7–118.3) | | Group C | 54.3 (35.4–73.3) | 50.7 (11.8–89.5) | 83.7 (51.2–116.1) | 115.3 (21.2–209.5) | | 0.116 | 0.307 | 0.004 | 0.010 |
| | ALP (mean [95% CI]) |
| | Group A | 170.7 (140.0–201.4) | 168.0 (142.3–193.7) | 148.1 (135.5–160.0) | 101.9 (89.6–114.1) | 0.001 | | Group B | 144.6 (85.2–204.0) | 157.2 (96.5–217.9) | 468.6 (341.2–596.0) | 317.0 (72.5–561.5) | | Group C | 157.3 (121.4–193.3) | 215.3 (−64.3–495.0) | 435.0 (270.7–599.2) | 523.0 (−405.6–1451.6) | | 0.497 | 0.386 | <0.001 | 0.020 |
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values of repeated measures ANOVA; values of one-way ANOVA; A: 50% resection; B: 75% resection; C: 85% resection; CI: confidence interval; : baseline; : one hour after resection; : one day after resection; : at sacrifice; INR: international normalized ratio; AST: aspartate transaminase; ALT: alanine transaminase; ALP: alkaline phosphatase.
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