Prevalence and Anatomic Distribution of Serrated and Adenomatous Lesions in Patients with Inflammatory Bowel Disease

Figure 1

Representative histology with H&E staining of (a) a sessile serrated adenoma or polyp (SSA/P) and (b) a traditional serrated adenoma (TSA). SSA/Ps generally show no or only focal conventional cytological dysplasia, have basal flattening or dilation of crypts, and have exaggerated apical cytoplasm creating a serrated morphology. TSAs have cytologic dysplasia throughout, have hypereosinophilic cytoplasm, and have a serrated morphology formed primarily by multiple adjacent complex buds (ectopic crypts).

(a)

(b)