Diagnostic Accuracy of Platelet Count and Platelet Indices in Noninvasive Assessment of Fibrosis in Nonalcoholic Fatty Liver Disease Patients

Table 2

Formulas for calculating noninvasive scores for fibrosis [12, 13].

Noninvasive index of fibrosis	Formula
NFS	1.675 + 0.037 × age (years) + 0.094 × BMI (kg/m^2) + 1.13 × IFG/diabetes (yes = 1, no = 0) + 0.99 × AST/ALT ratio; − 0.013 × platelet (×10^9/l) − 0.66 × albumin (g/dl)
APRI	[(AST/upper normal limit AST ) × 100]/platelets (10^9/L)
FIB-4	(Age × AST)/(platelets × sqr (ALT))
BARD	BMI ≥ 28 = 1p, AST/ALT ratio (AAR) ≥ 0.8 = 2p, DM = 1p

NFS: NAFLD fibrosis score; APRI: AST platelet ratio index; FIB-4: fibrosis-4; BARD: BMI, AST/ALT ratio, and diabetes [12, 13].