Preoperative Thrombocytopenia May Predict Poor Surgical Outcome after Extended Hepatectomy
Table 1
Clinicopathologic characteristics of patients who underwent extended hepatectomy.
Variables
Total
(n = 213)
Age (years)
60.8 ±11.7
Gender
Female/male
108/105
BMI (kg/m2)
25.53 ± 4.44
ASA score
Class 1
4 (2.5%)
Class 2
76 (46.9%)
Class 3
82 (50.6%)
Cirrhosis
Yes
7 (3.2%)
Indication of extended hepatectomy
Benign liver disease
9 (4.2%)
Primary malignancy
123 (57.7%)
Cholangiocarcinoma
105 (85.4)
Hepatocellular carcinoma
18 (14.6%)
Metastatic disease
81 (38.0%)
Preoperative chemotherapy
Yes
73 (35.8%)
Preoperative platelet count (x 109/L)
Mean (SD)
300.1 ± 121.5
Intraoperative blood loss (ml)
1638.21 ± 1535.49
Transfusion of RBC
Patient
60 (31.1%)
Unit
1.52 ± 3.34
Transfusion of FFP
Patient
44 (22.8%)
Unit
1.43 ± 3.64
Operation time (min)
293.78 ± 115.15
PHLF
56 (26.3%)
Grade A
16 (28.6%)
Grade B
14 (25.0%)
Grade C
26 (46.4%)
Major morbidity
57 (26.8%)
ICU stay (days)
8.14 ± 13.47
Hospitalization (days)
23.43 ± 16.68
30-day mortality
24 (11.3%)
BMI: body mass index; ASA: American Society of Anesthesiologists; SD: standard deviation; RBC: red blood cells; FFP: fresh-frozen plasma; PHLF: posthepatectomy liver failure; ICU: intensive care unit. Based on the ISGLS definition. Grades III and IV based on the Clavien-Dindo classification.
