Transcriptome Analysis of Porcine PBMCs Reveals the Immune Cascade Response and Gene Ontology Terms Related to Cell Death and Fibrosis in the Progression of Liver Failure

Table 3

KEGG pathways involved in the progression of ALF.

Name	Failure versus baseline			Dying versus baseline
	Mapped genes	Fold enrichment	FDR adjusted	Mapped genes	Fold enrichment	FDR adjusted
Cytokine-cytokine receptor interaction	25	3.0		38	2.5
Hematopoietic cell lineage	13	4.4		15	2.7
Lysosome	14	3.2		34	4.2
Rheumatoid arthritis	12	3.7		21	3.5
Malaria	9	4.6		14	3.9
Phagosome	15	2.7		26	2.5
Pertussis	10	3.7		20	3.9
NF-kappa B signaling pathway				19	3.1
Transcriptional misregulation in cancer				26	2.4
Chagas disease (American trypanosomiasis)				20	2.7
Leishmaniasis				14	3.3
TNF signaling pathway				19	2.5
Salmonella infection				16	2.8
Complement and coagulation cascades				14	2.8
Mineral absorption				10	3.4
Osteoclast differentiation				20	2.2
Legionellosis				12	2.8
Pentose phosphate pathway				7	4.6
Histidine metabolism				7	4.6