Serum Metabonomics Analysis of Liver Failure Treated by Nonbioartificial Liver Support Systems
Table 7
Clinical analysis of plasma exchange in the treatment of liver failure.
Liver failure type
Index
Mean (before and after)
Standard deviation (front and back)
The value of P
acute hepatic failure
ALT(U/L)
130.00, 76.33
147.77, 51.69
0.08
AST(U/L)
180.50, 100.17
117.18, 52.11
0.028
ALB(g/L)
31.82, 25.98
3.26, 1.06
0.042
ALP(U/L)
124.33, 93.00
24.19, 21.93
0.027
r-GT(U/L)
139.83, 79.83
30.65, 18.14
0.028
TBil(umol/L)
383.88, 206.82
127.49, 71.11
0.028
PT(s)
19.12, 16.87
2.50, 1.03
0.046
subacute hepatic failure
ALT(U/L)
427.67, 313.67
20.79, 104.18
0.285
AST(U/L)
343.67, 367.33
24.66, 267.99
1.00
ALB(g/L)
34.83, 28.00
2.60, 7.43
0.109
ALP(U/L)
117.00, 67.67
22.61, 21.50
0.109
r-GT(U/L)
56.33, 31.67
12.50, 13.58
0.109
TBil(umol/L)
633.90, 384.87
67.76, 80.85
0.109
PT(s)
37.77, 20.17
4.80, 1.80
0.109
acute-on-chronic liver failure
ALT(U/L)
272.90, 88.00
469.06, 56.50
0.008
AST(U/L)
371.20, 187.80
506.46, 193.74
0.005
ALB(g/L)
33.24, 29.85
1.92, 1.74
0.007
ALP(U/L)
74.00, 66.00
36.24, 25.79
0.541
r-GT(U/L)
70.50, 54.80
20.70, 13.10
0.047
TBil(umol/L)
559.37, 408.53
380.74, 321.44
0.005
PT(s)
20.24, 15.37
6.26, 1.53
0.028
Chronic liver failure
ALT(U/L)
37.8, 37.53
27.83, 18.69
0.955
AST(U/L)
97.20, 78.20
90.85, 76.31
0.019
ALB(g/L)
28.60, 27.86
6.21, 1.96
0.394
ALP(U/L)
89.00, 80.13
28.71, 23.39
0.053
r-GT(U/L)
41.40, 36.40
19.73, 18.53
0.033
TBil(umol/L)
319.73, 223.11
145.33, 79.61
0.001
PT(s)
24.06, 17.86
5.78, 2.60
0.001
Note.Compared with the preclinical indexes in the treatment of plasma exchange P < 0.05. Compared with the preclinical indexes in the treatment of plasma exchange P < 0.01. Compared with the preclinical indexes in the treatment of plasma exchange P 0.001. There was significant statistical significance.
