Macroscopic Portal Vein Thrombosis in HCC Patients
Table 2
Logistic regression model of PVT (No/Yes), on single variables (A). Final multiple logistic regression model in stepwise method of PVT (No/Yes), on all variables included together in the model (B). All models in total cohort.
Parameter
OR
se(OR)
p-value
95% C.I.
(A)
Platelet counts (103/μL)
1.002
0.001
0.003
1.001 to 1.004
Hemoglobin (g/dL)
0.899
0.034
0.005
0.835 to 0.969
GGTP (U/L)
1.001
0.0004
0.006
1.0003 to 1.0021
ALKP (U/L)
1.001
0.0004
0.002
1.0004 to 1.0019
Total Bilirubin (mg/dL)
1.042
0.021
0.04
1.002 to 1.084
Albumin (g/dL)
0.711
0.080
0.002
0.571 to 0.887
AFP (IU/mL)
≤100 [Ref. category]
1
>100
2.091
0.354
<0.001
1.500 to 2.913
MTD (cm)
1.178
0.027
<0.001
1.127 to 1.231
Tumor Nodule #
1.714
0.284
0.001
1.238 to 2.372
Cirrhosis (yes)
1.388
0.303
0.13
0.905 to 2.130
(B)
ALKP (U/L)
1.001
0.0004
0.02
1.0001 to 1.0017
Albumin (g/dL)
0.758
0.093
0.02
0.595 to 0.965
AFP (IU/mL)
≤100 [Ref. category]
1
>100
1.632
0.297
0.007
1.143 to 2.331
MTD (cm)
1.166
0.027
<0.001
1.114 to 1.219
Tumor Nodule #
1.558
0.281
0.01
1.094 to 2.219
All variables included in the model were considered as continuous, except the AFP which was considered as categorical. OR, odds ratio; se(OR), standard error of odds ratio; GGTP, gamma glutamyl transpeptidase; ALKP, alkaline phosphatase; AFP, alpha-fetoprotein; MTD, maximum tumor diameter; PVT, portal vein thrombosis.