Review Article
Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis
Table 2
Results of meta-regression for significant fibrosis.
| Covariate | Number | Pooled sensitivity | value | Pooled specificity | value | Joint value |
| Classification criteria | | | | | | | METAVIR score | 21 | 0.78 (0.75–0.83) | <0.01 | 0.79 (0.73–0.84) | <0.01 | 0.47 | Non-METAVIR score | 14 | 0.77 (0.70–0.83) | 0.83 (0.78–0.89) | Interval time | | | | | | | On the next day of liver biopsy | 11 | 0.76 (0.69–0.84) | <0.01 | 0.85 (0.79–0.90) | <0.01 | 0.29 | More than one day after liver biopsy | 24 | 0.78 (0.73–0.83) | 0.78 (0.74–0.83) | Average sample size | | | | | | | ⩾20 mm | 7 | 0.76 (0.66–0.86) | <0.01 | 0.79 (0.69–0.88) | <0.01 | 0.77 | Not ⩾ 20 mm | 28 | 0.78 (0.74–0.82) | 0.81 (0.77–0.85) | Region | | | | | | | Asian | 26 | 0.78 (0.73–0.82) | <0.01 | 0.83 (0.79–0.87) | 0.04 | 0.03 | Caucasian | 9 | 0.77 (0.68–0.85) | 0.72 (0.63–0.80) |
|
|