Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation

Table 3

Comparison of histological features between A-AIH and C-AIH patients.

	Acute	Chronic
G
0	0	1 (2.1%)	<0.001
1	1 (3.3%)	12 (25.0%)
2	2 (6.7%)	17 (35.4%)
3	21 (70.0%)	18 (37.5%)
4	6 (20.0%)	0
S
0	0	2 (4.2%)	0.135
1	10 (33.3%)	20 (41.7%)
2	3 (10.0%)	10 (20.8%)
3	7 (23.3%)	4 (8.3%)
4	10 (33.3%)	12 (25.0%)
Lobular inflammation
0	0	2 (4.2%)
1	17 (56.7%)	40 (80.3%)
2	6 (20.0%)	2 (4.2%)
3	7 (23.3%)	4 (8.3%)
Interface inflammation
0	4 (13.3%)	13 (27.1%)
1	5 (16.7%)	21 (43.8%)
2	14 (46.7%)	11 (22.9%)
3	7 (23.3%)	3 (6.3%)
Hepatocyte rosettes
No	2 (6.7%)	21 (43.8%)	<0.001
Yes	28 (93.3%)	27 (56.3%)
Periportal lymphocyte
0	0	0	<0.001
1	1 (3.3%)	19 (39.6%)
2	29 (96.7%)	29 (60.4%)
Periportal plasmocyte
0	1 (3.3%)	17 (35.4%)	<0.001
1	15 (50.0%)	27 (56.3%)
2	14 (46.7%)	4 (8.3%)
Periportal neutrophils
0	8 (26.7%)	28 (58.3%)
1	12 (40.0%)	16 (33.3%)
2	10 (33.3%)	4 (8.3%)
Periportal monocyte
0	0	0	<0.001
1	1 (3.3%)	19 (39.6%)
2	29 (96.7%)	29 (60.4%)
Periportal eosinocyte
0	13 (43.3%)	36 (75.0%)
1	17 (56.7%)	12 (25.0%)
2	0	0
Bile duct injury
0	5 (16.7%)	31 (64.6%)	<0.001
1	21 (70.0%)	17 (35.4%)
2	4 (13.3%)	0
Centrilobular necrosis
No	20 (66.7%)	44 (91.7%)
Yes	10 (33.3%)	4 (8.3%)
Lobular neutrophils
0	8 (26.7%)	40 (83.3%)	<
1	10 (33.3%)	5 (10.4%)
2	12 (40.0%)	3 (6.3%)
Lobular monocyte
0	8 (26.7%)	39 (81.3%)	<0.001
1	11 (36.7%)	7 (14.6%)
2	11 (36.7%)	2 (4.2%)
Lobular eosinocyte
0	19 (63.3%)	44 (91.7%)
1	10 (33.3%)	4 (8.3%)
2	1 (3.3%)	0
Eosinophilic body
No	22 (73.3%)	44 (91.7%)	0.05
Yes	8 (26.7%)	4 (8.3%)

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