Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children

Table 4

Comparison of obese children with and without liver steatosis diagnosed with measurement of intrahepatic lipid content using ¹HMRS.

Parameters	No liver steatosis; in ^1HMRS; median; Q1–Q3; ()	Liver steatosis; in ^1HMRS; median; Q1–Q3; ()
Gender, M/F	12/8	58/14	NS
IL-18 (pg/ml)	275; 205–340	342; 249–455	0.014
BMI (kg/m^2)	29; 27–32	28; 26–32	NS
Waist (cm)	96; 88–104	94; 90–105	NS
ALT (IU/l)	25; 16–45	37; 26–63	0.022
AST (IU/l)	24; 21–33	30; 25–39	0.013
GGT (IU/l)	17; 12–23	23; 18–31	0.016
Bilirubin (mg/dl)	0.7; 0.5–1.2	0.6; 0.4–0.8	NS
Total cholesterol (mg/dl)	172; 142–182	176; 150–192	NS
HDL-C (mg/dl)	50; 42–52	46; 39–55	NS
LDL-C (mg/dl)	92; 78–114	97; 78–121	NS
TG (mg/dl)	90; 61–120	115; 88–164	0.008
Glucose (mg/dl)	90; 85–95	92; 85–96	NS
Insulin (μIU/ml)	14; 8–18	15; 12–20	NS
HOMA-IR	3; 1.9–4	3.6; 2.8–4.6	NS
Uric acid (mg/dl)	5.7; 4.8–7	6; 5–6.8	NS
hsCRP (mg/l)	1; 0.7–2	1.3; 0.6–1.9	NS
Ferritin (ng/ml)	55; 29–73	57; 45–86	NS
A1AT (g/l)	1.4; 1.2–1.6	1.3; 1.2–1.5	NS
USG grade of steatosis	0.5; 0-1	1.5; 1-2	0.000