Research Article

Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma

Table 1

Correlation of Plexin C1 staining with clinicopathological characteristics of the patients.

Plexin C1 Staining
NNegativeWeakStrongP

Age
 ≤606510 (15.38%)12 (18.46%)43 (66.15%)
 >60255 (20%)6 (24%)14 (56%)0.67
Gender
 F163 (18.75%)4 (25%)9 (56.25%)
 M7412 (16.22%)14 (18.92%)48 (64.86%)0.799
Stage
 1&25211 (21.15%)8 (15.38%)33 (63.46%)
 3314 (12.9%)8 (25.81%)19 (61.29%)0.398
Grade
 Well-Differentiated6513 (20%)9 (13.85%)43 (66.15%)
 Poorly-Differentiated252 (8%)9 (36%)14 (56%)0.043
Disease Status
 HCC with cirrhosis165 (31.25%)2 (12.5%)9 (56.25%)
 HCC7410 (13.51%)16 (21.62%)48 (64.86%)0.204

N: number of cases. Correlation analyses were carried out with chi-square test. Plexin C1 staining was classified according to H-scores as follows: 0 = negative; 1-6 = weak; 7-12 = strong.