Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma
Table 1
Correlation of Plexin C1 staining with clinicopathological characteristics of the patients.
Plexin C1 Staining
N
Negative
Weak
Strong
P
Age
≤60
65
10 (15.38%)
12 (18.46%)
43 (66.15%)
>60
25
5 (20%)
6 (24%)
14 (56%)
0.67
Gender
F
16
3 (18.75%)
4 (25%)
9 (56.25%)
M
74
12 (16.22%)
14 (18.92%)
48 (64.86%)
0.799
Stage
1&2
52
11 (21.15%)
8 (15.38%)
33 (63.46%)
3
31
4 (12.9%)
8 (25.81%)
19 (61.29%)
0.398
Grade
Well-Differentiated
65
13 (20%)
9 (13.85%)
43 (66.15%)
Poorly-Differentiated
25
2 (8%)
9 (36%)
14 (56%)
0.043
Disease Status
HCC with cirrhosis
16
5 (31.25%)
2 (12.5%)
9 (56.25%)
HCC
74
10 (13.51%)
16 (21.62%)
48 (64.86%)
0.204
N: number of cases. Correlation analyses were carried out with chi-square test. Plexin C1 staining was classified according to H-scores as follows: 0 = negative; 1-6 = weak; 7-12 = strong.