Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes

Table 4

The 14 common DEGs for three GC cell lines after MYC-siRNA and the gene set hallmarks they were enriched in.

Hallmark Name:	Gene Symbol	Rank in Gene List	Rank Metric Score	Running (ES)
PROTEIN_SECRETION	BNIP3	1438	6.0E-01	0.522
UNFOLDED_PROTEIN_RESPONSE	SKIV2L2	1051	7.2E-01	0.508
UNFOLDED_PROTEIN_RESPONSE	SRPRB	1442	6.0E-01	0.506
REACTIVE_OXIGEN_SPECIES_PATHWAY	JUNB	1969	4.8E-01	0.491
G2M_CHECKPOINT	LBR	817	8.2E-01	0.451
OXIDATIVE_PHOSPHORYLATION	NDUFV2	1542	5.7E-01	0.444
APOPTOSIS	CDKN1B	2405	4.0E-01	0.420
PROTEIN_SECRETION	RAB22A	289	1.2E+15	0.408
CHOLESTEROL_HOMEOSTASIS	ATXN2	945	7.6E-01	0.382
CHOLESTEROL_HOMEOSTASIS	LGMN	445	1.1E+16	0.367
OXIDATIVE_PHOSPHORYLATION	ACAT1	840	8.1E-01	0.367
PROTEIN_SECRETION	TMED2	254	1.3E+16	0.326
DNA_REPAIR	AAAS	1109	7.0E-01	0.313
G2M_CHECKPOINT	NCL	328	1.2E+13	0.289

ES: enrichment score.