Canadian Journal of Gastroenterology and Hepatology / 2018 / Article / Tab 6

Research Article

Glucose Metabolism Changes in Patients with Chronic Hepatitis C Treated with Direct Acting Antivirals

Table 6

Predictors of significant (>5%) decrease of glycemia after DAA treatment.

Glycemia 5% decrease not achieved 
(mean±SEM or absolute (relative) counts
Glycemia 5% decrease achieved 
(mean±SEM or absolute (relative) counts
POR 95%CI

Age (years)60±161±10.3031.010.97-1.04

Male sex43 (45.3)25 (30.5)0.0440.530.26-0.99

BMI (kg/m2)26.9±0.4627.2±0.440.8071.0150.93-1.10

HCV RNA (IU/mL)2 380 969±443 9973 404 197±595 7640.0921.3690.91-2.06

Treatment experienced72 (75.8)66 (80.5)0.4521.320.64-2.71

Elastography (kPa)9.6±1.2311.1±1.410.8491.010.98-1.04

F4 fibrosis (elastography)45 (47.4)44 (55.0)0.3631.430.66-3.12

F3 fibrosis (elastography)28 (29.5)21 (26.3)0.8291.100.46-2.62

Thrombocytes x109/L172±7.7157±9.50.070.9970.994-1.001

APRI1.43±0.161.56±0.160.5581.0630.87-1.31

Baseline fasting glucose (mmol/L)5.7±1.87.2±2.7<0.00011.4311.177-1.740

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