Research Article

Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy

Table 3

Characteristics of chronic liver diseases alcohol related in male sex over time in Italy.

Characteristics2001 Study 2014 Study p-value
(n°=1,852)(n°=207)

Age (years), mean ± SD<0.001

BMI (kg/m2), mean ± SD<0.05

Area of origin
(i) Northern/Central Italy888 (45.8%)95 (45.9%)0.03
(ii) Southern Italy/Islands967 (52.2%)102 (49.3%)
(iii) Born abroad37 (2.0%)10 (4.8%)

Risk factors
(i) Alcohol intake alone710 (38.3%)100 (48.3%)0.015
(ii) Alcohol intake/HBsAg positive129 (7.0%)18 (8.7%)
(iii) Alcohol intake/anti-HCV positivity957 (51.7%)83 (40.1%)
(iv) Alcohol intake/HBsAg positive/anti-HCV positive56 (3.0%)6 (2.9%)

Diagnosis
(i) Chronic hepatitis1,231 (66.5%)117 (56.5%)0.004
(ii) Liver cirrhosis without HCC541 (29.2%)73 (35.3%)
(iii) Liver cirrhosis with HCC80 (4.3%)17 (8.2%)

BMI: body mass index. HCC: hepatocellular carcinoma.