Prophylactic Therapy of Silymarin (Milk Thistle) on Antituberculosis Drug-Induced Liver Injury: A Meta-Analysis of Randomized Controlled Trials

Table 2

Risk of bias assessment in the studies included for meta-analysis.

Study	Random sequence generation; (selection bias)	Allocatrion concealment; (selection bias)	Blinding of participants and personnel (performance bias)	Blinding of outcome assessment; (detection bias)	Incomplete outcome data(attrition bias)	Selective reporting; (reporting bias)	Other types of bias
Luangchosiri et al. 2015 [19]	L	L	L	L	L	L	U
Marjani et al. 2016 [20]	U	U	L	L	L	L	U
Zhang et al. 2016 [21]	L	H	H	H	L	L	U
Gu et al. 2015 [42]	U	H	H	H	L	L	U
Heo et al. 2017 [43]	L	L	L	L	L	L	U

Criteria defined for quality assessment are based on the Cochrane guidelines.
H: high risk of bias; L: low risk of bias; U: unclear risk of bias.