Clinical Aspects and Prognosis Evaluation of Cirrhotic Patients Hospitalized with Acute Kidney Injury

Table 3

Comparison of demographic, clinical, and laboratory screening variables at the end of the first month.

	Survivors (n=35)	Nonsurvivors (n = 14)	p value
Demographic
Age	54.6 (±11.6)	55 (±8.7)	0.915
Men	24 (68.6%)	10 (71.4%)	0.845
Women	11 (31.4%)	4 (28.6%)
Clinical
Child-Pugh	9.9(±2.1)	11.3(±1.5)	0.019
MELD	20.4 (±6.0)	25.1 (±8.7)	0.034
MELD-Na	23.1 (±6.4)	27.6 (±7.3)	0.037
ICA-AKI Stage			0.269
1	20 (57.1%)	8 (57.1%)
2	10 (28.6%)	6 (42.9%)
3	5 (14.3%)	0
Subdivision of stage 1 (n=28)			0.791
1a	6 (30%)	2 (25%)
1b	14 (70%)	6 (75:%)
AKI causes			0.609
Infection	14 (40%)	7 (50%)
Hypovolemia	11 (31.4%)	4 (28.6%)
Hepatorenal syndrome	2 (5.7%)	2 (14.3%)
Nephropathy	2 (5.7%)	0
Miscellaneous	2 (5.7%)	1 (7.1%)
Multiple	4 (11.4%)	0
Response to expansion treatment
Complete	24 (68.6%)	4 (28.6%)	0.001
Partial	7 (20%)	1 (7.1%)
Absent	4 (11.4%)	9 (64.3%)
Encephalopathy
Present	10 (28.6%)	4 (28.6%)	1.0
Absent	25 (71.4%)	10 (71.4%)
Ascites
Present	29 (82.9%)	12 (92.9%)	0.366
Absent	6 (17.1%)	1 (7.1%)
Laboratory
Creatinine (mg/dL)	2.2(±1.0)	1.8(±0.6)	0.165
Total bilirrubin (mg/dL)	1.72 (0.3-19.4)	6 (1.1-23.9)	0.028
Albumin (g/dL)	2.5 (±0.5)	2.4 (±0.5)	0.567
INR	1.5 (1.0-3.0)	2.0 (1.1-6.0)	0.012
Sodium (mEq/L)	133.2 (±5.4)	134.8 (±4.3)	0.329
C-Reactive Protein (mg/L)	30 (5-287)	31(13-197)	0.748

ICA-AKI, International Club of Ascites–Acute Kidney Injury.