Research Article

Clinical Aspects and Prognosis Evaluation of Cirrhotic Patients Hospitalized with Acute Kidney Injury

Table 4

Comparison of demographic, clinical, and laboratory screening variables at the end of three months.

Survivors (n =26)Nonsurvivors (n = 22)p value

Demographic
 Age55.3 (±12.1)54.1 (±9.5)0.726
 Men17 (65.4%)16 (72.7%)0.584
 Women9 (34.6%)6 (33.3%)
Clinical
Child-Pugh9.7(±2.1)10.9(±1.8)0.046
MELD19.3 (±6.1)24.6 (±7.6)0.012
MELD-Na21.7 (±6.6)27.5 (± 6.2)0.03
ICA-AKI Stage
 117 (65.4%)10 (56.3%)0.259
 26 (23.1%)10 (45.5%)
 33 (11.5%)2 (9.1%)
Subdivision of stage 1 (n=28)
 1a5 (29.4%)2 (20%)0.678
 1b12 (70.6%)8 (80%)
AKI causes
Infection10 (38.5%)10 (45.5%)0.058
Hypovolemia9 (34.6%)6 (27.3%)
Hepatorenal syndrome04 (18.2%)
Nephropathy2 (7.7%)0
Miscellaneous1 (3.8%)2 (9.1%)
Multiple4 (15.4%)0
Response to expansion treatment<0.0001
 Complete20 (76.9%)7 (31.8%)
 Partial5 (19.2%)3 (13.6%)
 Absent1 (3.8%)12 (54.5%)
Encephalopathy
Present6 (23.1%)7 (31.8%)0.361
Absent20 (76.9%)15 (68.2%)
Ascites
 Present21 (80.8%)12 (90.9%)0.532
 Absent5 (19.2%)2 (9.1%)
Laboratory
 Creatinine (mg/dL)2.0(±0.9)2.2(±2.2)0.525
 Total bilirrubin (mg/dL)1.6 (0.3-15.2)5 (0.4-23.9)0.020
 Albumin (g/dL)2.4 (±0.5)2.6 (±0.5)0.368
 INR1.5(1-3)1.9(1.1-7)0.067
 Sodium (mEq/L)134.1 (±5.2)133.4 (±5.2)0.681
 C-Reactive Protein (mg/L)30.4 (5-278)31.6(5-278)0.869

ICA-AKI, International Club of Ascites–Acute Kidney Injury.