Potential Role of HMGCS2 in Tumor Angiogenesis in Colorectal Cancer and Its Potential Use as a Diagnostic Marker

Figure 3

HMGCS2 inhibited tumor angiogenesis. (a) HUVECs were treated with conditional medium from HT-29 cells transfected with si-CTL and si-HMGCS2. Tube formation of HUVEC cells was visualized by phase contrast inverted microscope (100×). (b) Tube formation was assessed; the number of nodes per image was quantified and analyzed by two-way ANOVA, ∗∗p < 0.01. (c) Knockdown efficiency of HMGCS2 in HT-29 cells was verified by western blotting.

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