Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand?

Table 1

Techniques and criteria for assessing muscle mass, muscle strength, and physical performance.

	Sarcopenia criteria	Assessment technique	Adjustment	Cutoff values
				Men	Women
Muscle mass	EWGSOP [12], FNIH [87]	DXA	ASM	<20 kg	<15 kg
		DXA	ASM/height^2	<7.0 kg/m^2	<5.5 kg/m^2
		BIA	Predicted skeletal muscle mass equation (SM/height^2)	<8.87 kg/m^2	<6.42 kg/m^2
	AWGS [88]	BIA	ASM/height^2	<7.0 kg/m^2	<5.7 kg/m^2
		DXA	ASM/height^2	<7.0 kg/m^2	<5.4 kg/m^2
	FNIH [87]	DXA	ASM/BMI	<0.789 kg/BMI	<0.512 kg/BMI
	NAWGSLT [44]	CT	SMI	<50 cm^2/m^2	<39 cm^2/m^2
Muscle strength	EWGSOP [12]	Handgrip strength		<27 kg	<16 kg
	AWGS [88]			<28.0 kg	<18.0 kg
	FNIH [87]			<26 kg	<16 kg
Physical performance	EWGSOP [12], AWGS [88]	Gait speed	4-m course	≤0.8 m/s
		SPPB		≤8 point score

∗EWGSOP, The European Working Group on Sarcopenia in Older People; AWGS, The Asian Working Group for Sarcopenia; FNIH, The Foundation for the National Institutes of Health; NAWGSLT, North American Working Group on Sarcopenia in Liver Transplantation; DXA, dual energy X-ray absorptiometry; BIA, bioimpedance analysis; ASM, appendicular skeletal mass; SMI, skeletal muscle index; CT, computerized tomography; SPPB, short physical performance battery.