Prognostic Analysis of Different Metastatic Patterns in Invasive Intraductal Papillary Mucinous Neoplasm: A Surveillance, Epidemiology, and End Results Database Analysis
Table 1
Baseline and clinical characteristics of the study population.
No. (%) of patients
Characteristics
Nonorgan metastasis (n = 1228)
Isolated liver metastasis (n = 435)
Isolated lung metastasis (n = 185)
Isolated bone metastasis (n = 19)
Multiple (n = 175)
Other organ metastasis (n = 221)
Total (n = 2263)
value
Gender
0.107
Male
639 (52.0)
218 (50.1)
82 (44.3)
9 (47.4)
76 (43.4)
101 (45.7)
1125 (49.7)
Female
589 (48.0)
217 (49.9)
103 (55.7)
10 (52.6)
99 (56.6)
120 (54.3)
1138 (50.3)
Age (y)
0.097
<60
243 (19.8)
112 (25.7)
36 (19.5)
2 (10.5)
41 (23.4)
51 (23.1)
485 (21.4)
≥60
985 (80.2)
323 (74.3)
149 (80.5)
17 (89.5)
134 (76.6)
170 (76.9)
1778 (78.6)
Race
0.034
White
956 (77.9)
347 (79.8)
153 (82.7)
18 (94.7)
135 (77.1)
174 (78.7)
1783 (78.7)
Black
116 (9.4)
47 (10.8)
19 (10.3)
0 (0.0)
22 (12.6)
33 (14.9)
237 (10.5)
Yellow
147 (12.0)
41 (9.4)
13 (7.0)
1 (5.3)
18 (10.3)
14 (6.3)
234 (10.3)
Unknown
9 (0.7)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
0 (0.0)
9 (0.4)
Marital
0.119
Married
696 (56.7)
219 (50.3)
105 (56.8)
10 (52.6)
94 (53.7)
127 (57.5)
1251 (55.3)
Unmarried
470 (38.3)
194 (44.6)
63 (34.1)
9 (47.4)
73 (41.7)
85 (38.5)
894 (39.5)
Unknown
62 (5.0)
22 (5.1)
17 (9.2)
0 (0.0)
8 (4.6)
9 (4.1)
118 (5.2)
Primary site
<0.001
Head
704 (57.3)
120 (27.6)
65 (35.1)
6 (31.6)
39 (22.3)
46 (20.8)
980 (43.3)
Body/tail
270 (22.0)
168 (38.6)
65 (35.1)
8 (42.1)
77 (44.0)
84 (38.0)
672 (29.7)
Others
254 (20.7)
147 (33.8)
55 (29.7)
5 (26.3)
59 (33.7)
91 (41.2)
611 (27.0)
Surgery
<0.001
No
532 (43.3)
423 (97.2)
182 (98.4)
18 (94.7)
174 (99.4)
206 (93.2)
1535 (67.8)
Yes
696 (56.7)
12 (2.8)
3 (1.6)
1 (5.3)
1 (0.6)
15 (6.8)
728 (32.2)
Chemotherapy
<0.001
No
720 (58.6)
215 (49.4)
80 (43.2)
10 (52.6)
82 (46.9)
88 (39.8)
1195 (52.8)
Yes
508 (41.4)
220 (50.6)
105 (56.8)
9 (47.4)
93 (53.1)
133 (60.2)
1068 (47.2)
Radiotherapy
<0.001
No
1008 (82.1)
422 (97.0)
175 (94.6)
8 (42.1)
149 (85.1)
209 (94.6)
1971 (87.1)
Yes
220 (17.9)
13 (3.0)
10 (5.4)
11 (57.9)
26 (14.9)
12 (5.4)
292 (12.9)
Grade
<0.001
I
199 (16.2)
11 (2.5)
11 (5.9)
3 (15.8)
8 (4.6)
8 (3.6)
240 (10.6)
II
263 (21.4)
44 (10.1)
13 (7.0)
2 (10.5)
12 (6.9)
23 (10.4)
357 (15.8)
III
105 (8.6)
29 (6.7)
7 (3.8)
0 (0.0)
13 (7.4)
19 (8.6)
173 (7.6)
IV
15 (1.2)
2 (0.5)
0 (0.0)
0 (0.0)
0 (0.0)
2 (0.9)
19 (0.8)
Unknown
646 (52.6)
349 (80.2)
154 (83.2)
14 (73.7)
142 (81.1)
169 (76.5)
1474 (65.1)
MST (month)
24
4
6
4
2
4
9
Multiple mean metastases in at least 2 of the four organs (liver, lung, bone, and brain).Other organ metastasis mean metastases organs other than the liver, lungs, bones, and brain. MST mean median survival time.
